{"id":35035,"date":"2025-07-02T10:44:26","date_gmt":"2025-07-02T03:44:26","guid":{"rendered":"https:\/\/www.asianbioplex.com\/shop\/uncategorized\/v2g-ascorbyl-glucoside"},"modified":"2025-12-04T15:11:48","modified_gmt":"2025-12-04T08:11:48","slug":"v2g-ascorbyl-glucoside","status":"publish","type":"product","link":"https:\/\/www.asianbioplex.com\/en\/shop\/extracts-for-cosmetics\/v2g-ascorbyl-glucoside","title":{"rendered":"V2G (Ascorbyl Glucoside)"},"content":{"rendered":"

Ascorbyl Glucoside<\/strong><\/h3>\n
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V2G (Ascorbyl Glucoside) is a highly stable, high-purity vitamin C (98%) developed using an environmentally friendly bioprocess. This process uses the enzyme glycosyltransferase to attach a glucose molecule to pure vitamin C at the C-2 hydroxyl group, which is the most degradation-prone site in natural vitamin C.<\/p>\n

The product is a white to pale yellow powder with excellent stability against heat, pH changes, and metal-induced oxidation. Once applied to the skin, it is hydrolyzed by the enzyme \u03b1-glucosidase, releasing pure vitamin C to take effect. It helps reduce wrinkles by inhibiting collagen-degrading enzymes and promoting new collagen synthesis. It also brightens the skin by inhibiting melanin production and reducing existing pigmentation.<\/p>\n

This ingredient is ideal for those seeking youthful, radiant skin while protecting it from oxidative stress.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/article>\n\n\n\n<\/colgroup>\n\n\n\n\n\n\n\n\n\n\n\n
Subject<\/th>\nDescription<\/th>\n<\/tr>\n
Appearance<\/td>\nWhite powder<\/span><\/td>\n<\/tr>\n
pH<\/td>\n2.3 ~ 2.4<\/td>\n<\/tr>\n
Active ingredients<\/span><\/td>\nL-Ascorbic acid 2-glucoside \u226598.0%<\/td>\n<\/tr>\n
Applications<\/td>\nCosmetic products<\/td>\n<\/tr>\n
Suggested Concentration<\/td>\n2%<\/td>\n<\/tr>\n
Function<\/span><\/td>\nAnti-aging, Whitening agent<\/td>\n<\/tr>\n
INCI Name<\/td>\nAscorbyl Glucoside<\/td>\n<\/tr>\n
Storage conditions<\/td>\nSuitable: Keep\/store only in original container. Keep container tightly closed. Store in a cool dry place<\/td>\n<\/tr>\n
Shelf-Life<\/td>\n12 months from manufacturing date<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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\"Ascorbyl<\/p>\n

V2G (Ascorbyl Glucoside) stands out for its innovative process in which a glucose molecule is bonded to vitamin C at the C-2 hydroxyl group through a biotechnology method using a glucose-transferring enzyme that transfers glucose from starch to vitamin C. This results in a form of vitamin C with significantly higher stability than regular vitamin C and other vitamin C derivatives.<\/p>\n

Testing shows that when stored at pH 6.0 and 40\u00b0C for 60 days, V2G remains almost 100% intact, while regular vitamin C retains only about 20% and Sodium Ascorbyl Phosphate retains about 60%. It also demonstrates strong resistance to metal-ion oxidation; when exposed to Cu\u00b2\u207a, V2G retains 90% of its structure after 10 minutes, while regular vitamin C remains at only about 10%.<\/p>\n

When applied to the skin, the naturally occurring enzyme \u03b1-glucosidase gradually breaks down V2G, releasing pure vitamin C to act continuously. It effectively helps reduce signs of aging, brightens the complexion, and provides strong antioxidant protection. It is recommended for use at levels up to 2% in all types of skincare formulations.<\/p>\n

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Mechanism of Action of Ascorbyl Glucoside<\/h3>\n

Active Ingredient: Ascorbyl Glucoside (L-Ascorbic acid 2-glucoside)<\/p>\n

Chemical Structure:
Ascorbyl Glucoside is a compound formed by bonding a glucose molecule to vitamin C (L-Ascorbic acid) at the C-2 hydroxyl group\u2014 the position where natural vitamin C is most vulnerable to degradation. This glucose attachment protects vitamin C from oxidation, heat, humidity, and metal ions, resulting in far greater stability than regular vitamin C.<\/p>\n

Mechanisms of Action<\/h3>\n

1. Release of Pure Vitamin C on the Skin (Enzymatic Cleavage)
When V2G comes into contact with the skin, \u03b1-glucosidase\u2014an enzyme naturally present in human tissues such as the small intestine and skin\u2014hydrolyzes V2G, separating glucose and vitamin C. The released pure vitamin C penetrates the skin and works effectively as an anti-wrinkle and whitening agent. Tests show that V2G is completely hydrolyzed within 4 hours.<\/p>\n

2. Anti-wrinkle \u2013 Inhibition of Collagen-degrading Enzymes (Inhibition of MMP-1 Expression)
Sunlight (UVA, UVB, NIR) generates reactive oxygen species (ROS), which activate collagen-degrading enzymes (MMPs). These enzymes break down collagen and lead to wrinkles. V2G suppresses MMP-1 production in both UVA-exposed and non-exposed skin, with a stronger effect under UVA exposure. Its inhibitory effect increases with concentration.<\/p>\n

3. Anti-wrinkle \u2013 Enhancing Collagen Synthesis
Vitamin C released from V2G activates the enzyme Prolylhydroxylase by converting it from its inactive form (Fe\u00b3\u207a) to its active form (Fe\u00b2\u207a). This enzyme transforms proline into hydroxyproline, an essential component of strong collagen. Studies show that V2G at 1 mM is more effective at stimulating collagen production than other vitamin C derivatives. At 0.25 mM, V2G maintains consistent collagen-boosting activity for 5 days, while regular vitamin C declines daily.<\/p>\n

4. Brightening \u2013 Inhibition of Melanin Production (Inhibition of Melanogenesis)
Sun-induced ROS activates tyrosinase, the enzyme responsible for melanin formation. Tyrosinase converts tyrosine into DOPA and subsequently into melanin. V2G inhibits tyrosinase by binding to its copper ion (Cu\u00b2\u207a), reducing melanin synthesis. Tests show that V2G at 10 mM offers the strongest melanin-inhibiting effect, and over 3 days it maintains consistent performance, unlike regular vitamin C which declines each day.<\/p>\n

5. Reduction of Existing Pigmentation (Melanin Reduction \u2013 Lightening Effect)
Vitamin C released from V2G can convert dark melanin into its reduced (colorless) form, helping fade dullness, dark spots, and melasma. A clinical study using a lotion containing 2% V2G applied three times daily for 3 weeks showed reduced redness and pigmentation, with approximately 70% user satisfaction.<\/p>\n

6. Antioxidant Protection (ROS Scavenging)
V2G effectively neutralizes ROS caused by sunlight and pollution, protecting the skin from damage and premature aging. DPPH radical scavenging tests show that V2G has antioxidant activity comparable to pure vitamin C.<\/p>\n

Benefits and Applications<\/h3>\n