{"id":35090,"date":"2025-07-10T14:38:52","date_gmt":"2025-07-10T07:38:52","guid":{"rendered":"https:\/\/www.asianbioplex.com\/shop\/uncategorized\/bicosome-fs"},"modified":"2025-12-08T14:39:27","modified_gmt":"2025-12-08T07:39:27","slug":"bicosome-fs","status":"publish","type":"product","link":"https:\/\/www.asianbioplex.com\/en\/shop\/extracts-for-cosmetics\/bicosome-fs","title":{"rendered":"Bicosome\u00ae FS"},"content":{"rendered":"<h3>Bicosome\u00ae FS<\/h3>\n<article class=\"text-token-text-primary w-full focus:outline-none [--shadow-height:45px] has-data-writing-block:pointer-events-none has-data-writing-block:-mt-(--shadow-height) has-data-writing-block:pt-(--shadow-height) [&amp;:has([data-writing-block])&gt;*]:pointer-events-auto [content-visibility:auto] supports-[content-visibility:auto]:[contain-intrinsic-size:auto_100lvh] scroll-mt-[calc(var(--header-height)+min(200px,max(70px,20svh)))]\" dir=\"auto\" data-turn-id=\"request-689407d1-67d8-832e-8cf8-335daae6ff63-5\" data-testid=\"conversation-turn-488\" data-scroll-anchor=\"true\" data-turn=\"assistant\">\n<div class=\"text-base my-auto mx-auto pb-10 [--thread-content-margin:--spacing(4)] thread-sm:[--thread-content-margin:--spacing(6)] thread-lg:[--thread-content-margin:--spacing(16)] px-(--thread-content-margin)\">\n<div class=\"[--thread-content-max-width:40rem] thread-lg:[--thread-content-max-width:48rem] mx-auto max-w-(--thread-content-max-width) flex-1 group\/turn-messages focus-visible:outline-hidden relative flex w-full min-w-0 flex-col agent-turn\">\n<div class=\"flex max-w-full flex-col grow\">\n<div class=\"min-h-8 text-message relative flex w-full flex-col items-end gap-2 text-start break-words whitespace-normal [.text-message+&amp;]:mt-1\" dir=\"auto\" data-message-author-role=\"assistant\" data-message-id=\"ed18bc78-a003-43b0-8daa-7fef607340c3\" data-message-model-slug=\"gpt-5\">\n<div class=\"flex w-full flex-col gap-1 empty:hidden first:pt-[1px]\">\n<div class=\"markdown prose dark:prose-invert w-full break-words light markdown-new-styling\">\n<p data-start=\"0\" data-end=\"413\">Bicosome\u00ae FS (Filling-Up System) is a biomimetic skin-filling active developed using Bicosome\u00ae Technology by BICOSOME, S.L., Spain. It is produced from 99.5% natural soy-derived lipids, consisting of lecithin, hydrogenated phosphatidylcholine, and lysolecithin arranged in a special dual structure that includes an outer lipidic vesicle and internal discoidal structures, sized between 100\u2013400 nanometers.<\/p>\n<p data-start=\"415\" data-end=\"711\">This ingredient is designed to deliver bilayer-forming lipids into the intercellular spaces of the stratum corneum, helping to rebuild the skin\u2019s lipid matrix, reduce transepidermal water loss, improve elasticity, and enhance skin firmness. It also supports long-lasting repair of damaged skin.<\/p>\n<p data-start=\"713\" data-end=\"848\" data-is-last-node=\"\" data-is-only-node=\"\">It is ideal for individuals seeking to restore and strengthen the skin barrier, achieving firmer, smoother, and healthier-looking skin.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/article>\n<table dir=\"ltr\" border=\"1\" cellspacing=\"0\" cellpadding=\"0\">\n<colgroup>\n<col width=\"219\" \/>\n<col width=\"492\" \/> <\/colgroup>\n<tbody>\n<tr>\n<th>Subject<\/th>\n<th>Description<\/th>\n<\/tr>\n<tr>\n<td>Appearance<\/td>\n<td>Yellowish Liquid<\/td>\n<\/tr>\n<tr>\n<td>pH<\/td>\n<td>3.0 \u2013 6.0<\/td>\n<\/tr>\n<tr>\n<td>Composition<\/td>\n<td>&#8211; AQUA UP TO 100%<br \/>\n&#8211; LECITHIN 5-10%<br \/>\n&#8211; HYDROGENATED PHOSPHATIDYLCHOLINE 1-10%<br \/>\n&#8211; LYSOLECITHIN 1 \u2013 10%<\/td>\n<\/tr>\n<tr>\n<td>Applications<\/td>\n<td>Cosmetic products<\/td>\n<\/tr>\n<tr>\n<td>Suggested Concentration<\/td>\n<td>1 \u2013 3%<\/td>\n<\/tr>\n<tr>\n<td><span data-sheets-root=\"1\">Function<\/span><\/td>\n<td>Skin firming<\/td>\n<\/tr>\n<tr>\n<td>INCI Name<\/td>\n<td>Water, Lecithin, Hydrogenated<br \/>\nPhosphatidylcholine, Lysolecithin, Sodium<br \/>\nBenzonate, Citric Acid, Potassium Sorbate,<br \/>\nPhytic Acid, Tocophenol, Beta-Sitosterol,Squalene<\/td>\n<\/tr>\n<tr>\n<td>Storage conditions<\/td>\n<td><span data-sheets-root=\"1\">Store the product tightly closed in a dry and ventilated place, at not more than 8\u00baC. Protect from sunlight. The results of stability studies allow short periods of transport at 25\u00baC.<br \/>\nStirring the full content of the container before use or fractioning it is recommended to ensure adequate homogeneity.<br \/>\nUse soon after opening the package.<\/span><\/td>\n<\/tr>\n<tr>\n<td>Shelf-Life<\/td>\n<td>24 months from manufacturing date<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p data-start=\"0\" data-end=\"369\">Bicosome\u00ae FS stands out for its innovative Bicosome\u00ae Technology, which mimics the natural lipid structure of human skin. It features a unique dual structure composed of an outer lipidic vesicle that merges with the outermost skin layer, and internal discoidal structures that penetrate through intercellular spaces into the middle region of the stratum corneum.<\/p>\n<p data-start=\"371\" data-end=\"828\">ATR-FTIR spectroscopy using deuterium-labeled lipids demonstrated that Bicosome\u00ae FS disperses into the mid-stratum corneum. Additionally, GISAXS (Grazing Incidence Small Angle X-Ray Scattering) analysis showed that Bicosome\u00ae FS enhances lipid organization within the skin, creating new lamellar structures that integrate into the skin\u2019s lipid matrix\u2014mimicking the function of the basal epidermal layers responsible for forming the skin\u2019s lipid architecture.<\/p>\n<p data-start=\"830\" data-end=\"1141\" data-is-last-node=\"\" data-is-only-node=\"\">The product has passed comprehensive safety testing, confirming it to be non-irritant, non-phototoxic, and non-mutagenic. It is certified Vegan, Non-GMO, China NMPA compliant, and is not classified as a nanomaterial.<br data-start=\"1066\" data-end=\"1069\" \/>Recommended usage level: 1\u20133% in all types of skincare formulations.<\/p>\n<p>&nbsp;<\/p>\n<p data-start=\"72\" data-end=\"120\"><strong data-start=\"72\" data-end=\"118\">Mechanism of Action and Composition<\/strong><\/p>\n<article class=\"text-token-text-primary w-full focus:outline-none [--shadow-height:45px] has-data-writing-block:pointer-events-none has-data-writing-block:-mt-(--shadow-height) has-data-writing-block:pt-(--shadow-height) [&amp;:has([data-writing-block])&gt;*]:pointer-events-auto scroll-mt-[calc(var(--header-height)+min(200px,max(70px,20svh)))]\" dir=\"auto\" data-turn-id=\"request-692fea12-84e8-832a-a25d-d6b69cca41c9-2\" data-testid=\"conversation-turn-50\" data-scroll-anchor=\"true\" data-turn=\"assistant\">\n<div class=\"text-base my-auto mx-auto pb-10 [--thread-content-margin:--spacing(4)] @w-sm\/main:[--thread-content-margin:--spacing(6)] @w-lg\/main:[--thread-content-margin:--spacing(16)] px-(--thread-content-margin)\">\n<div class=\"[--thread-content-max-width:40rem] @w-lg\/main:[--thread-content-max-width:48rem] mx-auto max-w-(--thread-content-max-width) flex-1 group\/turn-messages focus-visible:outline-hidden relative flex w-full min-w-0 flex-col agent-turn\">\n<div class=\"flex max-w-full flex-col grow\">\n<div class=\"min-h-8 text-message relative flex w-full flex-col items-end gap-2 text-start break-words whitespace-normal [.text-message+&amp;]:mt-1\" dir=\"auto\" data-message-author-role=\"assistant\" data-message-id=\"ac9833f9-3845-404d-864a-9e00b15601f4\" data-message-model-slug=\"gpt-5-1\">\n<div class=\"flex w-full flex-col gap-1 empty:hidden first:pt-[1px]\">\n<div class=\"markdown prose dark:prose-invert w-full break-words light markdown-new-styling\">\n<p data-start=\"0\" data-end=\"77\"><strong data-start=\"0\" data-end=\"16\">Ingredients:<\/strong> Lecithin, Hydrogenated Phosphatidylcholine, and Lysolecithin<\/p>\n<p data-start=\"79\" data-end=\"178\">Structure and Composition:<br data-start=\"109\" data-end=\"112\" \/>Bicosome\u00ae FS is composed of three main natural soy-derived lipids:<\/p>\n<ul data-start=\"180\" data-end=\"577\">\n<li data-start=\"180\" data-end=\"299\">\n<p data-start=\"182\" data-end=\"299\">Lecithin (5\u201310%) \u2013 a phospholipid with a hydrophilic head and hydrophobic tail that can form bilayer structures<\/p>\n<\/li>\n<li data-start=\"300\" data-end=\"430\">\n<p data-start=\"302\" data-end=\"430\">Hydrogenated Phosphatidylcholine (1\u201310%) \u2013 a hydrogenated phosphatidylcholine with higher stability than standard lecithin<\/p>\n<\/li>\n<li data-start=\"431\" data-end=\"577\">\n<p data-start=\"433\" data-end=\"577\">Lysolecithin (1\u201310%) \u2013 a form of lecithin with a single fatty acid chain, conical in shape, and essential for forming discoidal structures<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"579\" data-end=\"686\">These three lipids are arranged using Bicosome\u00ae Technology, which creates a special dual structure:<\/p>\n<ul data-start=\"688\" data-end=\"847\">\n<li data-start=\"688\" data-end=\"755\">\n<p data-start=\"690\" data-end=\"755\">Outer Lipidic Vesicle \u2013 fuses with the outermost skin layer<\/p>\n<\/li>\n<li data-start=\"756\" data-end=\"847\">\n<p data-start=\"758\" data-end=\"847\">Internal Discoidal Structures \u2013 disc-shaped structures that penetrate between cells<\/p>\n<\/li>\n<\/ul>\n<hr data-start=\"849\" data-end=\"852\" \/>\n<h3 data-start=\"854\" data-end=\"882\"><strong data-start=\"858\" data-end=\"882\">Mechanisms of Action<\/strong><\/h3>\n<p data-start=\"884\" data-end=\"1296\">1. Penetration into the Stratum Corneum<br data-start=\"927\" data-end=\"930\" \/>Upon application, the outer vesicle of Bicosome\u00ae FS fuses with the skin\u2019s outermost layer, while the internal discoidal structures penetrate through intercellular spaces into the mid-stratum corneum. ATR-FTIR spectroscopy with deuterium-labeled lipids confirmed that Bicosome\u00ae FS distributes into the middle region of the stratum corneum (approximately 1\u20132 mm deep).<\/p>\n<p data-start=\"1298\" data-end=\"1553\">2. Refilling Effect \u2013 Filling Intercellular Spaces<br data-start=\"1352\" data-end=\"1355\" \/>The internal discoidal structures, containing bilayer-forming lipids, fill the inter-corneocyte spaces within the extracellular matrix, increasing the compactness and structural density of the skin.<\/p>\n<p data-start=\"1555\" data-end=\"1942\">3. Improvement of Skin Lipid Organization<br data-start=\"1600\" data-end=\"1603\" \/>GISAXS (Grazing Incidence Small Angle X-Ray Scattering) tests showed that skin treated with Bicosome\u00ae FS exhibits more organized lipid structures (higher peaks), indicating the formation of new lamellar structures integrating into the lipid matrix\u2014mimicking the function of basal epidermal layers in building the skin\u2019s lipid architecture.<\/p>\n<p data-start=\"1944\" data-end=\"2163\">4. Strengthening the Skin Barrier<br data-start=\"1981\" data-end=\"1984\" \/>By refilling gaps and improving lipid structure, Bicosome\u00ae FS reinforces the skin barrier, reduces transepidermal water loss (TEWL), and protects the skin from external irritants.<\/p>\n<p data-start=\"2165\" data-end=\"2356\">5. Enhancing Elasticity and Firmness<br data-start=\"2205\" data-end=\"2208\" \/>Improved lipid organization within the stratum corneum enhances the skin\u2019s elasticity and firmness, providing both immediate and long-term benefits.<\/p>\n<p data-start=\"2358\" data-end=\"2527\">6. Repairing Damaged Skin<br data-start=\"2387\" data-end=\"2390\" \/>Bicosome\u00ae FS helps repair damage caused by chemicals or external aggressors by restoring lipid structures and accelerating skin recovery.<\/p>\n<p data-start=\"2529\" data-end=\"2707\">7. Long-Lasting Effects<br data-start=\"2556\" data-end=\"2559\" \/>Because Bicosome\u00ae FS reaches the mid-stratum corneum and integrates into the lipid matrix, its effects persist even after discontinuing product use.<\/p>\n<hr data-start=\"2709\" data-end=\"2712\" \/>\n<h3 data-start=\"2714\" data-end=\"2747\"><strong data-start=\"2718\" data-end=\"2747\">Benefits and Applications<\/strong><\/h3>\n<ul data-start=\"2749\" data-end=\"3183\" data-is-last-node=\"\" data-is-only-node=\"\">\n<li data-start=\"2749\" data-end=\"2803\">\n<p data-start=\"2751\" data-end=\"2803\">Fills intercellular spaces in the outer skin layer<\/p>\n<\/li>\n<li data-start=\"2804\" data-end=\"2848\">\n<p data-start=\"2806\" data-end=\"2848\">Strengthens and repairs the skin barrier<\/p>\n<\/li>\n<li data-start=\"2849\" data-end=\"2886\">\n<p data-start=\"2851\" data-end=\"2886\">Reduces transepidermal water loss<\/p>\n<\/li>\n<li data-start=\"2887\" data-end=\"2923\">\n<p data-start=\"2889\" data-end=\"2923\">Improves elasticity and firmness<\/p>\n<\/li>\n<li data-start=\"2924\" data-end=\"2973\">\n<p data-start=\"2926\" data-end=\"2973\">Repairs damaged skin and accelerates recovery<\/p>\n<\/li>\n<li data-start=\"2974\" data-end=\"3023\">\n<p data-start=\"2976\" data-end=\"3023\">Long-lasting benefits even after stopping use<\/p>\n<\/li>\n<li data-start=\"3024\" data-end=\"3122\">\n<p data-start=\"3026\" data-end=\"3122\">Suitable for all skincare products, especially creams, serums, and barrier-repair formulations<\/p>\n<\/li>\n<li data-start=\"3123\" data-end=\"3154\">\n<p data-start=\"3125\" data-end=\"3154\">Recommended usage: 1\u20133%<\/p>\n<\/li>\n<li data-start=\"3155\" data-end=\"3183\" data-is-last-node=\"\">\n<p data-start=\"3157\" data-end=\"3183\" data-is-last-node=\"\">Suitable pH range: 3\u20139<\/p>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"z-0 flex min-h-[46px] justify-start\"><\/div>\n<div class=\"mt-3 w-full empty:hidden\">\n<div class=\"text-center\"><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/article>\n<div class=\"pointer-events-none h-px w-px\" aria-hidden=\"true\" data-edge=\"true\"><\/div>\n<h3 data-start=\"1444\" data-end=\"1642\"><img decoding=\"async\" class=\"size-medium wp-image-35087 aligncenter\" src=\"https:\/\/www.asianbioplex.com\/wp-content\/uploads\/2025\/07\/vitamin-drop-skin-cell-300x167.webp\" alt=\"vitamin-drop-skin-cell\" width=\"300\" height=\"167\" srcset=\"https:\/\/www.asianbioplex.com\/wp-content\/uploads\/2025\/07\/vitamin-drop-skin-cell-300x167.webp 300w, https:\/\/www.asianbioplex.com\/wp-content\/uploads\/2025\/07\/vitamin-drop-skin-cell-1024x569.webp 1024w, https:\/\/www.asianbioplex.com\/wp-content\/uploads\/2025\/07\/vitamin-drop-skin-cell-768x427.webp 768w, https:\/\/www.asianbioplex.com\/wp-content\/uploads\/2025\/07\/vitamin-drop-skin-cell-1536x853.webp 1536w, https:\/\/www.asianbioplex.com\/wp-content\/uploads\/2025\/07\/vitamin-drop-skin-cell-2048x1138.webp 2048w, https:\/\/www.asianbioplex.com\/wp-content\/uploads\/2025\/07\/vitamin-drop-skin-cell-600x333.webp 600w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/h3>\n<p data-start=\"0\" data-end=\"36\"><strong data-start=\"0\" data-end=\"36\">Research Study by BICOSOME, S.L.<\/strong><\/p>\n<p data-start=\"38\" data-end=\"90\">Short-Term &amp; Long-Lasting Effects Clinical Study<\/p>\n<p data-start=\"92\" data-end=\"456\">Method:<br data-start=\"103\" data-end=\"106\" \/>A study was conducted on 20 female volunteers aged 25\u201338 over a period of 16 days. A formula containing 2% Bicosome\u00ae FS and a control formula (without Bicosome\u00ae FS) were applied to the inner forearm once daily, for a total of 7 applications over 9 days. The subjects then stopped using the products, and results were monitored for an additional week.<\/p>\n<p data-start=\"458\" data-end=\"691\" data-is-last-node=\"\" data-is-only-node=\"\">Skin Barrier Function (TEWL), elasticity, and firmness were measured using a Tewameter TM 300 and a Cutometer SEM 575 during the application period (short-term efficacy) and again one week after discontinuation (long-lasting effect).<\/p>\n<p data-start=\"458\" data-end=\"691\" data-is-last-node=\"\" data-is-only-node=\"\"><img decoding=\"async\" class=\"wp-image-37345 aligncenter\" src=\"https:\/\/www.asianbioplex.com\/wp-content\/uploads\/2025\/07\/image-_12_-1-300x66.webp\" alt=\"Bicosome\u00ae FS\" width=\"732\" height=\"161\" srcset=\"https:\/\/www.asianbioplex.com\/wp-content\/uploads\/2025\/07\/image-_12_-1-300x66.webp 300w, https:\/\/www.asianbioplex.com\/wp-content\/uploads\/2025\/07\/image-_12_-1-1024x226.webp 1024w, https:\/\/www.asianbioplex.com\/wp-content\/uploads\/2025\/07\/image-_12_-1-768x169.webp 768w, https:\/\/www.asianbioplex.com\/wp-content\/uploads\/2025\/07\/image-_12_-1-600x132.webp 600w, https:\/\/www.asianbioplex.com\/wp-content\/uploads\/2025\/07\/image-_12_-1.webp 1424w\" sizes=\"(max-width: 732px) 100vw, 732px\" \/><\/p>\n<article class=\"text-token-text-primary w-full focus:outline-none [--shadow-height:45px] has-data-writing-block:pointer-events-none has-data-writing-block:-mt-(--shadow-height) has-data-writing-block:pt-(--shadow-height) [&amp;:has([data-writing-block])&gt;*]:pointer-events-auto scroll-mt-[calc(var(--header-height)+min(200px,max(70px,20svh)))]\" dir=\"auto\" data-turn-id=\"request-692fea12-84e8-832a-a25d-d6b69cca41c9-4\" data-testid=\"conversation-turn-54\" data-scroll-anchor=\"true\" data-turn=\"assistant\">\n<div class=\"text-base my-auto mx-auto pb-10 [--thread-content-margin:--spacing(4)] @w-sm\/main:[--thread-content-margin:--spacing(6)] @w-lg\/main:[--thread-content-margin:--spacing(16)] px-(--thread-content-margin)\">\n<div class=\"[--thread-content-max-width:40rem] @w-lg\/main:[--thread-content-max-width:48rem] mx-auto max-w-(--thread-content-max-width) flex-1 group\/turn-messages focus-visible:outline-hidden relative flex w-full min-w-0 flex-col agent-turn\">\n<div class=\"flex max-w-full flex-col grow\">\n<div class=\"min-h-8 text-message relative flex w-full flex-col items-end gap-2 text-start break-words whitespace-normal [.text-message+&amp;]:mt-1\" dir=\"auto\" data-message-author-role=\"assistant\" data-message-id=\"c819a78a-149b-4014-acac-0b2f3b6531c9\" data-message-model-slug=\"gpt-5-1\">\n<div class=\"flex w-full flex-col gap-1 empty:hidden first:pt-[1px]\">\n<div class=\"markdown prose dark:prose-invert w-full break-words light markdown-new-styling\">\n<p data-start=\"0\" data-end=\"12\"><strong data-start=\"0\" data-end=\"12\">Results:<\/strong><\/p>\n<p data-start=\"14\" data-end=\"68\">Short-Term Effects \u2013 During product application:<\/p>\n<ul data-start=\"69\" data-end=\"356\">\n<li data-start=\"69\" data-end=\"242\">\n<p data-start=\"71\" data-end=\"242\">Barrier Function (TEWL): Decreased by 7% after 7 applications<br data-start=\"136\" data-end=\"139\" \/>(A decrease in TEWL indicates reduced water loss through the skin and improved moisture retention.)<\/p>\n<\/li>\n<li data-start=\"243\" data-end=\"300\">\n<p data-start=\"245\" data-end=\"300\">Elasticity: Increased by 25% after 7 applications<\/p>\n<\/li>\n<li data-start=\"301\" data-end=\"356\">\n<p data-start=\"303\" data-end=\"356\">Firmness: Increased by 11% after 7 applications<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"358\" data-end=\"418\">Long-Lasting Effects \u2013 One week after discontinuation:<\/p>\n<ul data-start=\"419\" data-end=\"562\">\n<li data-start=\"419\" data-end=\"473\">\n<p data-start=\"421\" data-end=\"473\">Barrier Function (TEWL): Still decreased by 4%<\/p>\n<\/li>\n<li data-start=\"474\" data-end=\"519\">\n<p data-start=\"476\" data-end=\"519\">Elasticity: Remained increased by 20%<\/p>\n<\/li>\n<li data-start=\"520\" data-end=\"562\">\n<p data-start=\"522\" data-end=\"562\">Firmness: Remained increased by 8%<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"564\" data-end=\"985\"><strong data-start=\"564\" data-end=\"579\">Conclusion:<\/strong><br data-start=\"579\" data-end=\"582\" \/>Bicosome\u00ae FS demonstrates outstanding short-term and long-lasting benefits for skin improvement. After 7 applications, it reduced transepidermal water loss by 7%, increased elasticity by 25%, and improved firmness by 11%. Notably, even one week after stopping product use, the benefits persisted\u2014Barrier Function remained 4% better than baseline, elasticity remained elevated by 20%, and firmness by 8%.<\/p>\n<p data-start=\"987\" data-end=\"1316\" data-is-last-node=\"\" data-is-only-node=\"\">These findings confirm that Bicosome\u00ae FS not only delivers immediate short-term results but also enhances the skin\u2019s structure in a deep and lasting manner, with effects that continue even after discontinuation. This makes it highly suitable for developing skincare products that aim for both immediate and long-term performance.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/article>\n<p data-start=\"112\" data-end=\"134\"><strong data-start=\"112\" data-end=\"134\">Research Study<\/strong><\/p>\n<article class=\"text-token-text-primary w-full focus:outline-none [--shadow-height:45px] has-data-writing-block:pointer-events-none has-data-writing-block:-mt-(--shadow-height) has-data-writing-block:pt-(--shadow-height) [&amp;:has([data-writing-block])&gt;*]:pointer-events-auto scroll-mt-[calc(var(--header-height)+min(200px,max(70px,20svh)))]\" dir=\"auto\" data-turn-id=\"request-692fea12-84e8-832a-a25d-d6b69cca41c9-5\" data-testid=\"conversation-turn-56\" data-scroll-anchor=\"true\" data-turn=\"assistant\">\n<div class=\"text-base my-auto mx-auto pb-10 [--thread-content-margin:--spacing(4)] @w-sm\/main:[--thread-content-margin:--spacing(6)] @w-lg\/main:[--thread-content-margin:--spacing(16)] px-(--thread-content-margin)\">\n<div class=\"[--thread-content-max-width:40rem] @w-lg\/main:[--thread-content-max-width:48rem] mx-auto max-w-(--thread-content-max-width) flex-1 group\/turn-messages focus-visible:outline-hidden relative flex w-full min-w-0 flex-col agent-turn\">\n<div class=\"flex max-w-full flex-col grow\">\n<div class=\"min-h-8 text-message relative flex w-full flex-col items-end gap-2 text-start break-words whitespace-normal [.text-message+&amp;]:mt-1\" dir=\"auto\" data-message-author-role=\"assistant\" data-message-id=\"78c24fe3-edea-484f-98f9-9060cd136c02\" data-message-model-slug=\"gpt-5-1\">\n<div class=\"flex w-full flex-col gap-1 empty:hidden first:pt-[1px]\">\n<div class=\"markdown prose dark:prose-invert w-full break-words light markdown-new-styling\">\n<p data-start=\"28\" data-end=\"495\">A study conducted by the Department of Pharmaceutical Sciences at the University of Barcelona examined liposomal and lipid-based delivery systems for skincare, particularly systems using natural phospholipids such as lecithin and phosphatidylcholine. The research found that lipid structures resembling human skin lipids (biomimetic lipids) can penetrate the stratum corneum more effectively and enter intercellular spaces better than conventional active ingredients.<\/p>\n<p data-start=\"497\" data-end=\"989\" data-is-last-node=\"\" data-is-only-node=\"\">The study also showed that delivery systems with lamellar (multilayered) structures enhance lipid organization within the skin, strengthen the skin barrier, and significantly reduce transepidermal water loss. X-ray diffraction and FTIR spectroscopy confirmed that phospholipids delivered into the skin can merge with the skin\u2019s natural lipids, forming more ordered structures and improving skin elasticity and firmness\u2014particularly beneficial for dry skin or skin with a weakened barrier.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/article>\n<h6>Reference : Coderch, L., et al. &#8220;Ceramides and skin function: role in barrier properties.&#8221; American Journal of Clinical Dermatology, 2003, 4(2): 107-129<\/h6>\n<h3><b>Product Safety and Warranty Information<\/b><\/h3>\n<ul>\n<li>The product is manufactured through a certified process by leading organizations and has certification for industry standards that can be referenced.<\/li>\n<li>\n<div>The product is safe and can be used to support the registration of a cosmetic product.<\/div>\n<\/li>\n<li>The product is a raw material for industrial use, not a finished product. Users must have the knowledge and appropriate tools for using the raw material.<\/li>\n<li>The product is warranted according to the specifications, please refer to the <a href=\"https:\/\/www.asianbioplex.com\/en\/terms-conditions\">terms and conditions<\/a> for details.\n<ul>\n<li style=\"list-style-type: none\"><\/li>\n<\/ul>\n<ul>\n<li style=\"list-style-type: none\"><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<h3>(Price includes 7% VAT)<\/h3>\n<ul class=\"attr-list\">\n<li><span class=\"attr-name\" title=\"Part:\">From : Liquid<\/span><\/li>\n<li><span class=\"attr-name\" title=\"Place of Origin:\">Raw Material Origin : Spain<\/span><\/li>\n<li><span class=\"attr-name\" title=\"Grade:\">Grade :<\/span> Cosmetics<\/li>\n<li><span class=\"attr-name\" title=\"Botanical name:\">INCI Name : Water, Lecithin, Hydrogenated Phosphatidylcholine, Lysolecithin, Sodium<br \/>\nBenzonate, Citric Acid, Potassium Sorbate,Phytic Acid, Tocophenol, Beta-Sitosterol,Squalene<\/span><\/li>\n<li>Shelf Life : 24 months from the date of manufacture (UNOPENED)<\/li>\n<\/ul>\n<p><img decoding=\"async\" class=\"alignnone wp-image-35072\" src=\"https:\/\/www.asianbioplex.com\/wp-content\/uploads\/2025\/07\/Bicosome-logo-web-ok-retina-300x153.webp\" alt=\"Bicosome-logo\" width=\"107\" height=\"55\" srcset=\"https:\/\/www.asianbioplex.com\/wp-content\/uploads\/2025\/07\/Bicosome-logo-web-ok-retina-300x153.webp 300w, https:\/\/www.asianbioplex.com\/wp-content\/uploads\/2025\/07\/Bicosome-logo-web-ok-retina-600x306.webp 600w, https:\/\/www.asianbioplex.com\/wp-content\/uploads\/2025\/07\/Bicosome-logo-web-ok-retina.webp 677w\" sizes=\"(max-width: 107px) 100vw, 107px\" \/>\u00a0 \u00a0 \u00a0<img decoding=\"async\" class=\"alignnone wp-image-3612\" src=\"http:\/\/www.asianbioplex.com\/wp-content\/uploads\/2018\/08\/JP_GMP.jpg\" alt=\"\" width=\"67\" height=\"56\" \/><img decoding=\"async\" class=\"alignnone wp-image-3611\" src=\"http:\/\/www.asianbioplex.com\/wp-content\/uploads\/2018\/08\/JP-ISO.jpg\" alt=\"\" width=\"127\" height=\"51\" srcset=\"https:\/\/www.asianbioplex.com\/wp-content\/uploads\/2018\/08\/JP-ISO.jpg 362w, https:\/\/www.asianbioplex.com\/wp-content\/uploads\/2018\/08\/JP-ISO-300x120.jpg 300w, https:\/\/www.asianbioplex.com\/wp-content\/uploads\/2018\/08\/JP-ISO-360x145.jpg 360w\" sizes=\"(max-width: 127px) 100vw, 127px\" \/><\/p>\n","protected":false},"featured_media":35680,"template":"","meta":[],"product_brand":[],"product_cat":[144],"product_tag":[],"class_list":{"0":"post-35090","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-extracts-for-cosmetics","7":"pa_size-1-kg","8":"pa_size-10-ml","9":"pa_size-100-g","10":"pa_size-100-ml","11":"pa_size-30-g","12":"pa_size-50-ml","13":"pa_size-500-g","15":"first","16":"instock","17":"taxable","18":"shipping-taxable","19":"purchasable","20":"product-type-variable"},"yoast_head":"<!-- This site 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